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Nortriterpenoids from the stems and leaves of Schisandra viridis

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单位: [1]Huazhong Univ Sci & Technol, Hubei Key Lab Nat Med Chem & Resource Evaluat, Sch Pharm, Tongji Med Coll, Hangkonglu 13, Wuhan 430030, Peoples R China [2]Huazhong Univ Sci & Technol, Tongji Hosp, Dept Pharm, Wuhan 430030, Peoples R China
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关键词: Schisandra viridis Schisandraceae Nortriterpenoids Cytotoxicity

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An extensive phytochemical study on the stems and leaves of Schisandra viridis A.C. Smith led to the isolation of two novel highly oxygenated schinortriterpenoids, pre-schisanartanin P (1) and wuweizidilactone Q(2), together with four known ones (3-6). Their structures with absolute configurations were established on the basis of comprehensive spectroscopic methods, including HRESIMS, ID and 2D NMR analyses and ECD experiments. All isolates were evaluated for their in vitro cytotoxicities against HepG2, MCF-7 and HT-29 cancer cell lines, none of them showed significant activities. (C) 2017 Elsevier B.V. All rights reserved.

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出版当年[2016]版:
大类 | 3 区 医学
小类 | 3 区 药物化学 3 区 药学
最新[2025]版:
大类 | 3 区 医学
小类 | 3 区 药物化学 3 区 药学
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出版当年[2015]版:
Q2 PHARMACOLOGY & PHARMACY Q3 CHEMISTRY, MEDICINAL
最新[2023]版:
Q3 CHEMISTRY, MEDICINAL Q3 PHARMACOLOGY & PHARMACY

影响因子: 最新[2023版] 最新五年平均 出版当年[2015版] 出版当年五年平均 出版前一年[2014版] 出版后一年[2016版]

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第一作者单位: [1]Huazhong Univ Sci & Technol, Hubei Key Lab Nat Med Chem & Resource Evaluat, Sch Pharm, Tongji Med Coll, Hangkonglu 13, Wuhan 430030, Peoples R China
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