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Improved carotid lumen delineation on non-contrast MR angiography using SNAP (Simultaneous Non-Contrast Angiography and Intraplaque Hemorrhage) imaging

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单位: [1]Univ Washington, Dept Radiol, Seattle, WA 98109 USA [2]Huazhong Univ Sci & Technol, Dept Radiol, Tongji Med Coll, Tongji Hosp, 1095 Jiefang Ave, Wuhan 430000, Hubei, Peoples R China [3]Univ Washington, Dept Surg, Seattle, WA 98109 USA [4]Univ Washington, Dept Bioengn, Seattle, WA 98109 USA [5]Tsinghua Univ, Dept Bioengn, Beijing 100084, Peoples R China
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关键词: Magnetic resonance imaging MR angiography Carotid artery Image segmentation Intraplaque hemorrhage

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Purpose: Simultaneous Non-Contrast Angiography and Intraplaque Hemorrhage (SNAP) was developed for improved imaging of intraplaque hemorrhage (IPH). Its signal polarity also allows for non-contrast time-of-flight MR angiography (TOF). This study sought to compare SNAP and TOF in delineating carotid lumen using contrast-enhanced MRA (CE-MRA) as the reference standard. Materials and methods: Two hundred and eighty-nine matched slices from 15 arteries among 11 subjects (9 males and 2 females, mean age of 72.1 +/- 8.6 years) with lumina] stenosis on CE-MRA were studied. Cross-sectional slices centered around the carotid bifurcation were matched between the three MRA techniques (SNAP, TOF, and CE-MRA) and classified as slices with or without plaque (focal wall thickness >= 1.5 mm) by additional black blood vessel wall MRI. Lumen area was measured using a Sobel gradient map for TOF and CE-MRA (magnitude images) and a polarity map for SNAP. Agreement between techniques for measuring lumen area and percent stenosis was evaluated using intraclass correlation coefficient (ICC) and paired t-test. Results: Among the 289 matched slices, SNAP showed a higher agreement with CE-MRA than TOF for measuring lumen area (ICC: 0.93 vs. 0.83; p = 0.03). Agreement with CE-MBA was high for both SNAP and TOF in slices without plaque (ICC: 0.91 vs. 0.89; p > 0.05) but favored SNAP over TOF in slices with plaque (ICC: 0.93 vs. 0.80; p = 0.02). Conclusion: SNAP, assisted by signal polarity information, demonstrated a higher agreement with CE-MRA in delineating carotid lumen compared to TOF, particularly in slices with plaque where flow conditions may be more complex.

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出版当年[2018]版:
大类 | 3 区 医学
小类 | 3 区 核医学
最新[2025]版:
大类 | 4 区 医学
小类 | 4 区 核医学
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出版当年[2017]版:
Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
最新[2023]版:
Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

影响因子: 最新[2023版] 最新五年平均 出版当年[2017版] 出版当年五年平均 出版前一年[2016版] 出版后一年[2018版]

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第一作者单位: [1]Univ Washington, Dept Radiol, Seattle, WA 98109 USA [*1]850 Republican St Rm 124, Seattle, WA 98109 USA
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通讯机构: [1]Univ Washington, Dept Radiol, Seattle, WA 98109 USA [*1]850 Republican St Rm 124, Seattle, WA 98109 USA
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