Evaluation of mechanical and biological properties of akermanite/poly-ether-ether-ketone composite fabricated by high-temperature laser powder bed fusion
单位：[1]State Key Laboratory of Materials Processing and Die & Mould Technology, School of Materials Science and Engineering, Huazhong University of Science and Technology, Wuhan 430074, China[2]Department of Orthopedic Surgery,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,China华中科技大学同济医学院附属同济医院外科学系骨科[3]Wuhan Zeqing Technology Co. Ltd., Wuhan 430074, China
High-temperature laser bed powder fusion (HT-LPBF) technology is an ideal method for processing poly-ether-ether-ketone (PEEK) implants with personalized bionic structures, but the biological inertia of PEEK limits its medical applications. In this study, we evaluated the mechanical and biological properties of a novel akermanite (AKM)/PEEK composite for HT-LPBF. The results showed that tiny AKM particles are evenly attached to the surface of the PEEK particle. The delayed peak crystallization temperature and stable sintering window ensure the processing feasibility of the AKM/PEEK composites. The tensile strength and Young's modulus are in the range of 30.83-98.73 MPa and 2.27-3.71 GPa, respectively, which can match the properties of cancellous bones and meet their implanting requirement. The CCK-8 experiments demonstrated the biocompatibility of the composites and the good proliferation of bone marrow stromal cells. The dense hydroxyapatite network layer and petal-like hydroxyapatite demonstrates biological activity, indicating that the composite has a good potential in the orthopedics fields.
基金：
National Natural Science Foundation of China [52105341]; Key Research andDevelopment Plan of Hubei Province [2021BAA211, 2022BAA030]; China Postdoctoral Science Foundation [2020M682406]; China Electric Power Research Institute [PDB51201901707]; Fundamental Research Funds for the Central Universities [2019kfyRCPY044, 2021GCRC002]; Program for HUST Academic Frontier Youth Team [2018QYTD04]
第一作者单位：[1]State Key Laboratory of Materials Processing and Die & Mould Technology, School of Materials Science and Engineering, Huazhong University of Science and Technology, Wuhan 430074, China
通讯作者：
推荐引用方式(GB/T 7714)：
Chen Zhiyuan,Wang Haoze,Su Jin,et al.Evaluation of mechanical and biological properties of akermanite/poly-ether-ether-ketone composite fabricated by high-temperature laser powder bed fusion[J].INTERNATIONAL JOURNAL OF BIOPRINTING.2023,9(3):doi:10.18063/ijb.699.
APA：
Chen, Zhiyuan,Wang, Haoze,Su, Jin,Shu, Zixing,Hou, Jiayi...&Shi, Yusheng.(2023).Evaluation of mechanical and biological properties of akermanite/poly-ether-ether-ketone composite fabricated by high-temperature laser powder bed fusion.INTERNATIONAL JOURNAL OF BIOPRINTING,9,(3)
MLA：
Chen, Zhiyuan,et al."Evaluation of mechanical and biological properties of akermanite/poly-ether-ether-ketone composite fabricated by high-temperature laser powder bed fusion".INTERNATIONAL JOURNAL OF BIOPRINTING 9..3(2023)
