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Cadonilimab (PD-1/CTLA-4 Bi-specific Antibody) and Chemoradiotherapy in Locoregionally-advanced Nasopharyngeal Carcinoma

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研究单位: [1]Sun Yat-sen University [2]Akeso Pharmaceuticals, Inc. [3]The First Affiliated Hospital of Bengbu Medical College,Bengbu,Anhui,China,233000 [4]The First Affiliated Hospital of University of Science and Technology of China,Hefei,Anhui,China,230041 [5]Cancer Hospital Chinese Academy of Medical Sciences,Beijing,Beijing,China [6]Fujian Cancer Hospital,Fuzhou,Fujian,China [7]Dongguan Peaple's Hospital,Dongguan,Guangdong,China [8]Sun Yat-sen Memorial Hospital,Guangzhou,Guangdong,China,510000 [9]SUN YAT-SEN UNIVERSITY cANCER CENTER,Guangzhou,Guangdong,China,510060 [10]Shenzhen People's Hospital,Shenzhen,Guangdong,China,518001 [11]Zhongshan city Peaple's Hospital,Zhongshan,Guangdong,China [12]Cancer Hospital of Guangxi Medical University,Nanning,Guangxi,China [13]Cancer Hospital of Guizhou Medical University,Guiyang,Guizhou,China [14]Renmin Hospital of Wuhan University,Wuhan,Hubei,China,430000 [15]Zhongnan Hospital of Wuhan University,Wuhan,Hubei,China,430071 [16]Hubei Province Cancer Hosiptal,Wuhan,Hubei,China [17]Tongji Hospital Affiliated with Tongji Medical College of Huazhong University of Science and Technology,Wuhan,Hubei,China [18]Union Hospital Affiliated with Tongji Medical College of Huazhong University of Science and Technology,Wuhan,Hubei,China [19]Hunan Cancer Hospital,Changsha,Hunan,China,410000 [20]Xiangya Hospital Central South University,Changsha,Hunan,China

关键词: immunotherapy PD-1/CTLA-4 Bi-specific Antibody Chemoradiotherapy

研究目的:
The trial aimed to compare cadonilimab combined with induction chemotherapy plus concurrent chemoradiotherapy (IC+CCRT) versus IC+CCRT alone in high-risk locoregionally-advanced nasopharyngeal carcinoma (LANPC).

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