研究单位:[1]Biochemistry Department, Chinese PLA General Hospital[2]The First Affiliated Hospital of Fujian Medical University Fuzhou, China[3]Sun Yat-Sen University Cancer Center Guangzhou,China华中科技大学同济医学院附属同济医院肿瘤科[4]Shandong University Qilu Hospital Jinan, China[5]Fudan University Shanghai Cancer Center Shanghai, China[6]Tianjin Cancer Hospital Tianjin, China[7]Xinjiang Medical University Cancer Center Urumchi, China[8]Tongji Hospital Tongji Medical Colege of HUST Wuhan,China华中科技大学同济医学院附属同济医院[9]Zhongshan Hospital Xiamen University Xiamen, China
Aim of this study is to provide specimens for establishing reference values of HE4 in an apparently healthy Chinese population using the Roche Elecsys HE4 assay tested on variety of Elecsys and cobas brand immunoassay analyzers. This reference range will be compared to population of subjects who have signs and symptoms of various benign and malignant diseases, including ovarian cancer. This reference range will also be compared to the levels of HE4 in individual subjects who have been diagnosed with ovarian cancer and are being followed longitudinally for recurrence or progression of their disease.