In this work, we discovered a new phenomenon-asymptomatic COVID-19 infection, or covert case, during the pandemic. All the 3 patients had a history of exposure, with no symptoms, and no abnormalities were found in computed tomography scan or lab tests. Except for case 2, the other patients' severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) nucleic acid tests were negative. But their anti-SARS-COV-2 nucleocapsid antibody showed a dynamic trend, consistent with the process of virus infection and clearance. A growing number of asymptomatic or covert cases need more attention. Lack of surveillance may lead to another outbreak. We hope to demonstrate our cases to attract the attention of governments or health authorities that covert cases should be the focus as well.
基金：
Science and Technology Department, Hubei province [2020FCA035]; COVID-19 Prompt Response Research Special Project from Huazhong University of Science and Technology [2020kfyXGYJ023]
基金编号：2020FCA0352020kfyXGYJ023
语种：
外文
被引次数：
WOS：
PubmedID：
中科院(CAS)分区：
出版当年[2020]版：
大类|3 区医学
小类|3 区医学：研究与实验3 区移植4 区细胞与组织工程
最新[2025]版：
大类|4 区医学
小类|3 区移植4 区细胞与组织工程4 区医学：研究与实验
JCR分区：
出版当年[2019]版：
Q2TRANSPLANTATIONQ2MEDICINE, RESEARCH & EXPERIMENTALQ3CELL & TISSUE ENGINEERING
最新[2024]版：
Q2MEDICINE, RESEARCH & EXPERIMENTALQ2TRANSPLANTATIONQ3CELL & TISSUE ENGINEERING
第一作者单位：[1]Huazhong Univ Sci & Technol, Tongji Hosp, Tongji Med Coll, Dept Emergency, 095 Jie Fang Ave, Wuhan 430030, Peoples R China
通讯作者：
通讯机构：[1]Huazhong Univ Sci & Technol, Tongji Hosp, Tongji Med Coll, Dept Emergency, 095 Jie Fang Ave, Wuhan 430030, Peoples R China
推荐引用方式(GB/T 7714)：
Hu Tao,Liu Xiao,Yin Qinan,et al.Are RNA-Based Tests Sufficient for COVID-19 Diagnosis? An Inspiration of Three Asymptomatic Cases[J].CELL TRANSPLANTATION.2021,30:doi:10.1177/0963689720985453.
APA：
Hu, Tao,Liu, Xiao,Yin, Qinan,Duan, Xingting&Yan, Li.(2021).Are RNA-Based Tests Sufficient for COVID-19 Diagnosis? An Inspiration of Three Asymptomatic Cases.CELL TRANSPLANTATION,30,
MLA：
Hu, Tao,et al."Are RNA-Based Tests Sufficient for COVID-19 Diagnosis? An Inspiration of Three Asymptomatic Cases".CELL TRANSPLANTATION 30.(2021)
