A subgroup of COVID-19 patients develop very severe disease with requirement for ICU treatment, ventilation, and ECMO therapy. Laboratory tests indicate that the immune and clotting system show marked alterations with hyper-activation, hyper-inflammation, cytokine storm development. Furthermore, organ-specific biomarkers demonstrate the involvement of cardiac muscle, kidney, and liver dysfunction in many patients. In this article the use of laboratory biomarkers is discussed with regard to their use for diagnosis, disease progression, and risk assessment. (C) 2020 The British Infection Association. Published by Elsevier Ltd. All rights reserved.
基金:
Universities Giessen Marburg Lung Center; German Center for Lung Disease (DZL German Lung Center) [82DZL00502]; Universities Giessen and Marburg Lung Cen-ter; German Center for Lung Research, University Hospital Giessen and Marburg (UKGM); Deutsche Forschungsgemeinschaft (DFG) [KFO 309, SK 317/1-1, 428518790, SFB 1021]; State Scholarships Foundation (IKY), Partnership Agreement (PA) 2014-2020; European Union (European Social Fund-ESF) through the Operational Program "Human Resources Development, Education and Lifelong Learning 2014-2020
Skevaki Chrysanthi,Fragkou Paraskevi C.,Cheng Chongsheng,et al.Laboratory characteristics of patients infected with the novel SARS-CoV-2 virus[J].JOURNAL OF INFECTION.2020,81(2):205-212.doi:10.1016/j.jinf.2020.06.039.
APA:
Skevaki, Chrysanthi,Fragkou, Paraskevi C.,Cheng, Chongsheng,Xie, Min&Renz, Harald.(2020).Laboratory characteristics of patients infected with the novel SARS-CoV-2 virus.JOURNAL OF INFECTION,81,(2)
MLA:
Skevaki, Chrysanthi,et al."Laboratory characteristics of patients infected with the novel SARS-CoV-2 virus".JOURNAL OF INFECTION 81..2(2020):205-212