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Effect of male age on the outcome of in vitro fertilization: oocyte donation as a model

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单位: [1]Huazhong Univ Sci & Technol, Reprod Med Ctr, Tongji Hosp, Tongji Med Coll, Wuhan 430074, Peoples R China
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关键词: In vitro fertilization Live birth rate Male age Oocyte donation Pregnancy loss

摘要:
To assess the influence of male age on the outcome of oocyte donation cycles. A total 103 oocyte donation cycles of 70 couples (male aged 26 to 57) were examined, all of which were performed with conventional in vitro fertilization using fresh ejaculation sperm. Main outcome measures were fertilization rate, clinical pregnancy, live birth rates and pregnancy loss. A total 122 cryopreserved embryo transfer were performed, resulting in 34 cycles resulted in clinical pregnancy and 27 live births. No significant correlation was found between male age and fertilization rate. No significant difference was found in male age between the patients who achieved clinical pregnancy and live birth and those who did not. All the pregnancy loss occurred in cycles where the male was older than 37, however, when the cycles were divided into two groups according to whether or not male age older than 37, no statistically significant difference was not found in pregnancy loss rate. Aging of the male has no significant impact on fertilization, pregnancy or live birth in oocyte donation cycles, but may be associated with pregnancy loss.

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出版当年[2011]版:
大类 | 4 区 医学
小类 | 4 区 遗传学 4 区 妇产科学
最新[2025]版:
大类 | 3 区 医学
小类 | 2 区 生殖生物学 3 区 遗传学 3 区 妇产科学
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出版当年[2010]版:
Q3 OBSTETRICS & GYNECOLOGY Q4 GENETICS & HEREDITY
最新[2023]版:
Q1 OBSTETRICS & GYNECOLOGY Q2 GENETICS & HEREDITY Q2 REPRODUCTIVE BIOLOGY

影响因子: 最新[2023版] 最新五年平均 出版当年[2010版] 出版当年五年平均 出版前一年[2009版] 出版后一年[2011版]

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第一作者单位: [1]Huazhong Univ Sci & Technol, Reprod Med Ctr, Tongji Hosp, Tongji Med Coll, Wuhan 430074, Peoples R China
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