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ADAMTS13: more than a regulator of thrombosis

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收录情况： ◇ SCIE

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单位： [1]Huazhong Univ Sci & Technol, Tongji Med Coll, Tongji Hosp, Dept Obstet & Gynaecol, Wuhan, Peoples R China [2]Zhengzhou First Peoples Hosp, Dept Urol, Zhengzhou, Peoples R China

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关键词： ADAMTS13 Expression Inflammation Angiogenesis Extracellular matrix

摘要：

ADAMTS13, a plasma reprolysin-like metalloprotease, proteolyzes von Willebrand factor (VWF). ADAMTS13 is primarily synthesized by hepatic stellate cells (HSCs), and mainly regulates thrombogenesis by cleaving VWF. Recent studies demonstrate that ADAMTS13 also plays a role in the down-regulation of inflammation, regulation angiogenesis, and degradation of extracellular matrix. The purpose of this review is to introduce the state of progress with respect to some of the theorized roles of ADAMTS13.

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出版当年[2015]版：

大类 | 4 区医学

小类 | 4 区血液学

最新[2025]版：

大类 | 4 区医学

小类 | 4 区血液学

JCR分区：

出版当年[2014]版：

Q3 HEMATOLOGY

最新[2023]版：

Q3 HEMATOLOGY

影响因子： 1.7 最新[2023版] 1.8 最新五年平均 1.918 出版当年[2014版] 1.677 出版当年五年平均 1.679 出版前一年[2013版] 1.846 出版后一年[2015版]

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第一作者单位： [1]Huazhong Univ Sci & Technol, Tongji Med Coll, Tongji Hosp, Dept Obstet & Gynaecol, Wuhan, Peoples R China

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