Two pairs of chlorine-containing phenylpropanoid enantiomers (1a/1b and 2a/2b) were isolated from the rhizomes of Aconis tatarinowii. Interestingly, these optical isomers (1a/1b and 2a/2b) were co-existed in the same plant, which were characterized as the first halogen-containing natural products from the genus Acorus. Their structures and absolute configurations were elucidated by a combination of spectroscopic analysis and a single-crystal X-ray diffraction, assisted by a modified Mosher's method. The phenylpropanoid isomers (1a/1b and 2a/2b) were evaluated for their antioxidant activities using DPPH assay and cytotoxic activities against five human cancer cell lines. (C) 2017 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. par rights reserved.
基金：
Program for New Century Excellent Talents in University, State Education Ministry of China [NCET-2008-0224]; National Natural Science Foundation of China [31370372, 81573316, 31570361, 31200258]
第一作者单位：[1]Huazhong Univ Sci & Technol, Tongji Hosp Affiliated, Tongji Med Coll, Wuhan 430030, Hubei, Peoples R China
通讯作者：
推荐引用方式(GB/T 7714)：
Lu Yuan-Yuan,Gong Xue-Peng,Xue Yong-Bo,et al.Two pairs of chlorine-containing phenylpropanoid enantiomers from Acorus tatarinowii[J].CHINESE CHEMICAL LETTERS.2017,28(7):1460-1464.doi:10.1016/j.cclet.2017.03.024.
APA：
Lu, Yuan-Yuan,Gong, Xue-Peng,Xue, Yong-Bo,Zhu, Hu-Cheng,Li, Xiao-Nian...&Zhang, Yong-Hui.(2017).Two pairs of chlorine-containing phenylpropanoid enantiomers from Acorus tatarinowii.CHINESE CHEMICAL LETTERS,28,(7)
MLA：
Lu, Yuan-Yuan,et al."Two pairs of chlorine-containing phenylpropanoid enantiomers from Acorus tatarinowii".CHINESE CHEMICAL LETTERS 28..7(2017):1460-1464
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