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Outcomes of patients with anemia and renal dysfunction in hospitalized heart failure with preserved ejection fraction (from the CN-HF registry)

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收录情况： ◇ ESCI

作者：
Jin, Xuejuan[1] * ; Cao, Juan[1,2,13] ; Zhou, Jun[1] ; Wang, Yanyan[1] ; Han, Xueting[1] ; Song, Yu[1] ; Fan, Yuyuan[1,2,13] ; Chen, Zhenyue[3,42] ; Xu, Dingli[4] ; Yang, Xinchun[5] ; Dong, Wei[6] ; Li, Liwen[7,30] ; Chen, Li[2,13] ; Zhong, Qiaoqing[8,10] ; Fu, Micheal[9] ; Hu, Kai[1] ; Zhou, Jingmin[1] ; Ge, Junbo[1] ; Lu, Yingmin[11] ; Zhang, Guohui[12] ; Gu, Huimin[14] ; Wei, Meng[15] ; Chen, Lianglong[16] ; Wang, Jun[17] ; Yang, Zhenyu[18] ; Jin, Huigen[19] ; Li, Xianliang[20] ; Qiao, Zengyong[21] ; Yang, Yingjun[22] ; Zhao, Yulan[23] ; Jia, Ru[24] ; Hong, Bin[25] ; Yuan, Fang[26] ; Wang, Jufei[27] ; Ma, Jin[28] ; Xu, Yu[29] ; Wahafu, Mahmud[31] ; Yu, Qin[32] ; Wang, Changqian[33] ; Ruan, Changwu[34] ; Fu, Honggang[35] ; Liu, Xuebo[36] ; Xu, Xin[37] ; Chen, Shaoping[38] ; Liu, Qiliang[39] ; Shi, Bei[40] ; Xu, Jiahong[41] ;
单位： [1]Fudan Univ, Zhongshan Hosp, Shanghai Inst Cardiovasc Dis, Dept Cardiol, 180 Fenglin Rd, Shanghai 200032, Peoples R China [2]Affiliated Hosp North Sichuan Med Coll, North Sichuan Med Coll, Dept Cardiol, Nanchong, Sichuan, Peoples R China [3]Shanghai Jiao Tong Univ, Ruijin Hosp, Dept Cardiol, Sch Med, Shanghai, Peoples R China [4]Southern Med Univ, Nanfang Hosp, Dept Cardiol, Guangzhou, Peoples R China [5]Capital Med Univ, Heart Ctr, Beijing Chaoyang Hosp, Beijing, Peoples R China [6]Chinese Peoples Liberat Army Gen Hosp, Dept Cardiol, Beijing, Peoples R China [7]Guangdong Acad Med Sci, Guangdong Gen Hosp, Guangdong Cardiovasc Inst, Dept Cardiol, Guangzhou, Peoples R China [8]First Peoples Hosp Chenzhou, Dept Cardiol, Chenzhou, Peoples R China [9]Univ Gothenburg, Sahlgrenska Univ Hosp, Dept Med, Sect Cardiol,Ostra Hosp, Gothenburg, Sweden [10]Chenzhou 1 Peoples Hosp, Chenzhou, Peoples R China [11]Shanghai Jiao Tong Univ, Xin Hua Hosp, Sch Med, Chongming Branch, Shanghai, Peoples R China [12]Zhenjiang First Peoples Hosp, Zhengzhou, Peoples R China [13]North Sichuan Med Coll, Affiliated Hosp, Nanchong, Peoples R China [14]First Peoples Hosp Kunshan, Kunshan, Peoples R China [15]Shanghai Sixth Peoples Hosp, Shanghai, Peoples R China [16]Fujian Med Univ, Union Hosp, Fuzhou, Fujian, Peoples R China [17]Jingan Dist Cent Hosp Shanghai, Shanghai, Peoples R China [18]Wuxi Peoples Hosp, Wuxi, Jiangsu, Peoples R China [19]Putuo Peoples Hosp Shanghai, Shanghai, Peoples R China [20]Zhangjiagang Hosp Tradit Chinese Med, Zhangjiagang, Peoples R China [21]Shanghai Fengxian Dist Cent Hosp, Shanghai, Peoples R China [22]Jiashan First Peoples Hosp, Jiashan, Peoples R China [23]Zhenzhou Univ, Affiliated Hosp 2, Zhengzhou, Peoples R China [24]4 Hosp 1946 Jinan Shandong, Jinan, Peoples R China [25]Shanghai Qingpu Dist Cent Hosp, Shanghai, Peoples R China [26]Shanghai Chest Hosp, Shanghai, Peoples R China [27]Fenghua Hosp, Fenghua, Peoples R China [28]Tongji Univ, Yangpu Hosp, Shanghai, Peoples R China [29]Henan Prov Peoples Hosp, Zhengzhou, Peoples R China [30]Guangdong Gen Hosp, Guangzhou, Peoples R China [31]Second Peoples Hosp Kashgar Prefecture, Kashi, Xinjiang, Peoples R China [32]Dalian Univ, Zhongshan Hosp, Dalian, Peoples R China [33]Shanghai Ninth Peoples Hosp, Shanghai, Peoples R China [34]Shanghai Eighth Peoples Hosp, Shanghai, Peoples R China [35]Fuyuan Peoples Hosp, Qujing, Peoples R China [36]Tongji Univ, Shanghai East Hosp, Shanghai, Peoples R China [37]Wuxi 2 Peoples Hosp, Wuxi, Jiangsu, Peoples R China [38]Changhai Hosp Shanghai, Shanghai, Peoples R China [39]Putuo Dist Ctr Hosp, Shanghai, Peoples R China [40]Hosp Zhunyi Med Coll, Zunyi, Guizhou, Peoples R China [41]Tongji Univ, Tongji Hosp, Wuhan, Hubei, Peoples R China [42]Shanghai Jiao Tong Univ, Sch Med, Rui Jin Hosp, Shanghai, Peoples R China
出处：
DOI： 10.1016/j.ijcha.2019.100415

关键词： Heart failure Heart failure with preserved ejection fraction Anemia Renal dysfunction

摘要：
Background: Although a large number of studies on heart failure with reduced ejection fraction (HFrEF) have found that anemia and renal dysfunction (RD) independently predicted poor outcomes, there are still few reports on patients with heart failure with preserved ejection fraction (HFpEF). Methods: Clinical data of HFpEF patients registered in the China National Heart Failure Registration Study (CN-HF) were evaluated and the clinical features of patients with or without anemia/RD were compared to explore the impact of anemia and RD on all-cause mortality and all-cause re-hospitalization. Results: 1604 patients with HFpEF were enrolled, the prevalence of anemia was 51.0%. Although anemia was associated with increased risk of all-cause mortality and all-cause re-hospitalization in univariate COX regression (p < 0.05), multivariate COX model confirmed that anemia was not independently associated with all-cause mortality (hazard ratio (HR) 1.14, 95% confidence interval (CI) 0.85-1.52, p - 0.386] and all-cause re-hospitalization (HR 1.13,95% CI 0.96-1.33, p - 0.152). Similarly, RD was not an independent predictor of all-cause mortality (HR 1.18, 95% CI 0.88-1.57, p - 0.269) and all-cause re-hospitalization (HR 0.94, 95% CI 0.79-1.12, p - 0.488) as assessed in the adjusted COX regression model. The interaction between RD and anemia on end-points events was also not statistically significant. However, anemia was associated with increased all-cause rehospitalization in patients with New York Heart Association (NYHA) class III-IV. Conclusions: In patients with HFpEF from CN-HF registry, anemia was common, but was not an independent predictor of all-cause mortality and all-cause re-hospitalization, except for the all-cause re-hospitalization in patients with NYHA class III-IV. (C) 2019 The Authors. Published by Elsevier B.V.

基金：
National Science & Technology Pillar Program, 12th 5-year plan of China [2011BAI11B10]
语种：
外文
被引次数：
WOS：
PubmedID：
中科院(CAS)分区：
出版当年[2018]版：
无
最新[2025]版：
大类 | 3 区 医学
小类 | 3 区 心脏和心血管系统
JCR分区：
出版当年[2017]版：
无
最新[2023]版：
Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

影响因子： 最新[2023版] 最新五年平均 出版当年[2017版] 出版当年五年平均 出版前一年[2016版]

第一作者：
第一作者单位： [1]Fudan Univ, Zhongshan Hosp, Shanghai Inst Cardiovasc Dis, Dept Cardiol, 180 Fenglin Rd, Shanghai 200032, Peoples R China
通讯作者：
推荐引用方式(GB/T 7714)：
Jin Xuejuan,Cao Juan,Zhou Jun,et al.Outcomes of patients with anemia and renal dysfunction in hospitalized heart failure with preserved ejection fraction (from the CN-HF registry)[J].IJC HEART & VASCULATURE.2019,25:doi:10.1016/j.ijcha.2019.100415.
APA：
Jin, Xuejuan,Cao, Juan,Zhou, Jun,Wang, Yanyan,Han, Xueting...&Xu, Jiahong.(2019).Outcomes of patients with anemia and renal dysfunction in hospitalized heart failure with preserved ejection fraction (from the CN-HF registry).IJC HEART & VASCULATURE,25,
MLA：
Jin, Xuejuan,et al."Outcomes of patients with anemia and renal dysfunction in hospitalized heart failure with preserved ejection fraction (from the CN-HF registry)".IJC HEART & VASCULATURE 25.(2019)

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