The intrinsic limits of conventional ultrasound microbubble contrast agent greatly promoted the development and application of various nanomaterials for more efficient cancer ultrasound theranostics. Considerable successes have been achieved in the field of ultrasound molecular imaging and targeted therapy for tumor based on nanoparticulate theranostic agents. This review summarizes and discusses the emerging development on exploring organic and inorganic nanomaterials for ultrasound-based tumor diagnositic applications, and as synergistic agents for ultrasound targeted therapy in fighting cancer. The relationship between structure/composition and functionality of nanomaterials for ultrasound theranostic is discussed and revealed in detail. Finally, the further development and challenges facing clinical implementation of ultrasound nanomedicine are discussed. As a highly promising and valuable tumor-specific theranostic methodology, it is believed that ultrasound nanomedicine would pave a novel but efficient way for combating cancer.
第一作者单位：[1]Huazhong Univ Sci & Technol,Tongji Hosp,Sino German Tongii Caritas Res Ctr Ultrasound Med,Tongji Med Coll,Dept Med Ultrasound,1095 Jiefang Ave,Wuhan 430030,Hubei,Peoples R China
通讯作者：
推荐引用方式(GB/T 7714)：
Zhou Li-Qiang,Li Pan,Cui Xin-Wu,et al.Ultrasound nanotheranostics in fighting cancer: Advances and prospects[J].CANCER LETTERS.2020,470:204-219.doi:10.1016/j.canlet.2019.11.034.
APA：
Zhou, Li-Qiang,Li, Pan,Cui, Xin-Wu&Dietrich, Christoph F..(2020).Ultrasound nanotheranostics in fighting cancer: Advances and prospects.CANCER LETTERS,470,
MLA：
Zhou, Li-Qiang,et al."Ultrasound nanotheranostics in fighting cancer: Advances and prospects".CANCER LETTERS 470.(2020):204-219
医学