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Evaluation of myocardial strain and aortic elasticity in patients with bicuspid aortic valve

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收录情况： ◇ SCIE

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单位： [1]Huazhong Univ Sci & Technol, Tongji Hosp, Dept Med Ultrasound, Tongji Med Coll, Wuhan 430030, Peoples R China [2]Bengbu Med Coll, Affiliated Hosp 1, Dept Med Ultrasound, Bengbu 233004, Peoples R China [3]Wenzhou Med Univ, Affiliated Hosp 1, Dept Med Ultrasound, Wenzhou 325000, Peoples R China

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关键词： aorta elasticity speckle tracking imaging bicuspid aortic valve

摘要：

This study evaluated the myocardial strain and aortic elasticity in patients with bicuspid aortic valve (BAV) and then investigated the relation between them. Thirty-nine patients (30 males; mean age 44 +/- 19 years; range 6 to 75 years) with BAV were recruited as BAV group, and 29 age- and sex-matched healthy controls (21 males; mean age 42 +/- 11 years; range 20 to 71 years) served as control group. Aortic strain, distensibility and stiffness index were derived using M-mode echocardiography. Left ventricular global myocardial strain was acquired with speckle-tracking echocardiography. Correlation between aortic elasticity and myocardial strain was also analyzed. The results showed that aortic stiffness was higher (17.5 +/- 14.0 vs. 5.3 +/- 2.7, P < 0.001), and aortic strain (4.9 +/- 4.7 vs. 11.0 +/- 4.1, P < 0.001) and distensibility (1.8 +/- 2.1 vs. 3.7 +/- 1.6, P < 0.001) were lower significantly in BAV group than in control group. Global circumferential strain (-19.1 +/- 4.2 vs.-22.5 +/- 3.7, P < 0.001), radial stain (29.8 +/- 14.9 vs. 38.0 +/- 8.8, P < 0.001) and longitudinal stain (-18.4 +/- 3.4 vs.-20.8 +/- 3.5, P < 0.001) were significantly lower in BAV group than in control group. There was weak association between aortic elasticity and myocardial strain. These findings indicated BAV patients manifest reduced myocardial strain which had weak relationship with aortic elastic lesion.

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出版当年[2015]版：

大类 | 4 区医学

小类 | 4 区生化与分子生物学

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无

JCR分区：

出版当年[2014]版：

Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY

最新[2023]版：

无

影响因子： 0 最新[2023版] 0 最新五年平均 0.834 出版当年[2014版] 0.749 出版当年五年平均 0.779 出版前一年[2013版] 0.838 出版后一年[2015版]

第一作者：

第一作者单位： [1]Huazhong Univ Sci & Technol, Tongji Hosp, Dept Med Ultrasound, Tongji Med Coll, Wuhan 430030, Peoples R China [2]Bengbu Med Coll, Affiliated Hosp 1, Dept Med Ultrasound, Bengbu 233004, Peoples R China

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