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Correlation between age and thickness of Descemet's membrane in Chinese people

中国人角膜后弹力层厚度与年龄的相关性研究(英文)

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单位: [1]中国湖北省武汉市华中科技大学同济医学院附属同济医院眼科 [2]Department of Ophthalmology,Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology,Wuhan 430030,Hubei Province,China.
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关键词: cornea Descemet's membrane thickness age

摘要:
 AIM: To examination the thickness of Chinese Descemet's membrane and investigate the correlation with age. METHODS: Twenty - seven normal corneas with ages ranging from 0. 2 to 78y old were collected. All specimens were stained with Hematoxylin and Eosin,and viewed and photographed at ×400 through a calibrated Motic light photomicroscope. Four measurement sites on each specimen micrograph were chosen and the boundary of Descemet's membrane was designated manually, then the Descemet's membrane thickness was measured by the software of Motic Images Plus 2. 0 automatically. The relationship between Descemet's membrane thickness and age was analyzed by using linear regression methods.  RESULTS: The thickness of Chinese Descemet's membrane various from 1. 78 to 9. 30 μm,averaged 4. 63± 2. 00 μm. There is a highly significant positive correlation between age and thickness of Descemet's membrane ( r = 0. 776,P = 0. 000) . The estimated equation that best describes the relationship of thickness with age can be expressed as: Thickness ( μm) = 2. 010+0. 063y.  CONCLUSION: There is a significant positive association between age and the thickness of Descemet's membrane in Chinese people.

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基金编号: 81200661,81470606

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第一作者单位: [1]中国湖北省武汉市华中科技大学同济医学院附属同济医院眼科
通讯作者:
通讯机构: [2]Department of Ophthalmology,Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology,Wuhan 430030,Hubei Province,China.
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