单位：[1]Department of Obstetrics and Gynecology, Aviation General Hospital, Chaoyang District, Beijing, China[2]College of Medicine,Chinese Academy of Sciences, Huairou District, Beijing, China[3]Department of Epidemiology, College of Public Health, Zhengzhou University, Zhengzhou, Henan, 450001, China[4]Cancer Center of the First Hospital of Jilin University,Changchun, Jilin 130021,China[5]Department of Medical Oncology, Fujian Cancer Hospital, Fujian Medical University Cancer Hospital, Fuzhou, Fujian 350014, China[6]Department of Gastrointestinal Surgery, Affiliated Tumor Hospital of Guangxi Medical University, Nanning, Guangxi 530021, China[7]Department of Surgery, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510080,China中山大学附属第一医院[8]Department of Clinical Nutrition, West China Hospital of Sichuan University, Chengdu, Sichuan 610041,China四川大学华西医院[9]Department of Gastrointestinal Oncology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer,Tianjin Key Laboratory of Cancer Prevention and Therapy, Tianjin 30060, China[10]Department of Nutrition and Metabolism of Oncology, Affiliated Provincial Hospital of Anhui Medical University, Hefei, Anhui 230031, China[11]Department of Clinical Nutrition,the First Hospital of Hefei Medical University, Shijiazhuang, Hebei 050031, China[12]Department of Gastrointestinal Surgery, Institute of Gastroenterology, the First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan 650032, China昆明医科大学附属第一医院[13]Department of Clinical Nutrition, the First People's Hospital of Kashi, Xinjiang 844000, China[14]Zhongshan Chenxinghai Hospital(Affiliated ZhongshanChenxinghai Hospital of Guangdong Medical University), Zhongshan, Guangdong 528400, China[15]Department of Clinical Nutrition, Chongqing General Hospital, Chongqing 40014, China[16]Department of Colorectal and Anal Surgery, Huizhou Municipal Central Hospital, Huizhou, Guangdong 516001, China[17]Department of Radiation and Medical Oncology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei 430071, China[18]Department of Oncology, Xingtai People's Hospital, Hebei Medical University, Xingtai, Hebei 054031, China[19]The First Department of Tumor Hospital of Harbin Medical University, Harbin,Heilongjiang 150085, China[20]Department of Nutrition, Guangdong General Hospital, Guangdong Academy of Medical Sciences,Guangzhou, Guangdong 510080, China广东省人民医院[21]Department of Oncology, Affiliated Cancer Hospital of Zhengzhou University and Henan Cancer Hospital, Zhengzhou, Henan 450008, China河南省肿瘤医院[22]Department of General Surgery, Xiangya Hospital, Central South University,Changsha, Hunan 410008, China[23]Comprehensive Oncology Department, Cancer Hospital, Chinese Academy of Medical Sciences,Beijing 100021, China[24]Abdominal Surgery Department, Cancer Institute and Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100021, China[25]The Fourth Affiliated Hospital, Harbin Medical University, Harbin,Heilongjiang 150001, China[26]Cancer Center, the First People's Hospital of Foshan, Foshan, Guangdong 528000, China[27]Department of Gastrointestinal Tumor Surgery, the First Affiliated Hospital Xiamen University, Xiamen, Fujian 361001, China[28]Department of Nutrition, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China[29]Department of Nutrition, Tianjin Third Central Hospital, Tianjin 300170, China[30]Department of Surgery, the First Affiliated Hospital Jinan University, Guangzhou, Guangdong 510632, China[31]Department of General Surgery, Nanjing Drum Tower Hospital,the Affiliated Hospital of Nanjing University Medical School, Nanjing, Jiangsu 210008, China[32]Department of Gastrointestinal Surgery, the First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530021, China[33]Department of Radiation and Medical University, People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, Guangxi 5300021, China[34]Department of Clinical Nutrition, Peking University Cancer Hospital and Institute, Beijing 100142, China[35]Department of Nutrition, Third Affiliated Hospital Kunming Medical College, Tumor Hospital of Yunnan Province, Kunming 650118, China[36]Department of Surgery,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,China华中科技大学同济医学院附属同济医院外科学系外科学系[37]Department of Nutrition, Guangzhou Red Cross Hospital, Guangzhou, Guangdong 510220, China[38]Department of Radiotherapy, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu,Sichuan 610041, China四川省人民医院四川省肿瘤医院[39]Department of Clinical Nutrition, Clifford Hospital, Guangzhou University of Chinese Medicine,Guangzhou, Guangdong 510632, China广东省中医院[40]Department of Digestive Diseases, Xijing Hospital, Fourth Military Medical University,Xi'an, Shanxi 710032, China[41]Cancer Center, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, China[42]Department of Nutrition, Daping Hospital & Research Institute of Surgery, Third Military Medical University, Chongqing 400042, China[43]Department of Gastrointestinal Surgery, Department of Clinical Nutrition, Beijing Shijitan Hospital, Capital Medical University/The 9th Clinical Medical College, Peking University, Beijing 100038, China
Background Malnutrition is common among cancer patients,but few studies have evaluated the nutritional status among gynecological cancer patients in China.This study aimed to assess the nutritional status of women with gynecological cancer using the patient-generated subjective global assessment (PG-SGA).Methods Data for gynecological cancer patients treated at 44 tertiary hospitals were retrieved from a multicenter study on tumor nutrition.The R Software was used for statistical analyses.Univariate analyses of PG-SGA scores were performed using the Chi-squared test for categorical variables and the Wilcoxon-rank sum test or Kruskal-Wallis test for continuous variables,as appropriate.The significance level was 0.05.Results Data for 1962 women with three types of gynecological cancer (cervical,uterine and ovarian cancer) were used for the data analysis.The median PG-SGA score was 4 (interquartile range,IQR:1,8),the median participants' age was 51 (IQR:46,59) years old,and the patients had a median BMI of 22.9 (IQR:20.7,25.4).The percentages of women who had a medical co-morbidity,or had undergone any radical resection,chemotherapy,or radiotherapy were approximately 27.7％,55.4％,52.5％,and 30.2％,respectively.The levels of serum albumin and high density lipoprotein cholesterol (HDL-C) were 40.1g/L (IQR:36.8,43.1) and 1.2mmol/L (IQR:1.0,1.5),respectively.The identified risk factors for malnutrition based on the PG-SGA score were age (0.05±0.01,p =0.002),BMI (-0.34±0.04,p ＜ 0.001),having a medical co-morbidity (0.95±0.33,p =0.004),receiving radiotherapy (1.52±0.31,p ＜ 0.001),the serum albumin level (-0.18±0.03,p ＜ 0.001),and the HDL-C (-1.12±0.35,p =0.001) as indicated by a linear regression analysis.Conclusions A higher PG-SGA score is positively associated with the age of the patient,having a medical co-morbidity,and receiving radiotherapy,and is negatively related to the patients' BMI and serum albumin and HDL-C levels.
基金：
This study was financially supported by the
National Key Research and Development Program (No.
2017YFC 1309200).
基金编号：No.2017YFC 1309200
语种：
中文
第一作者：
第一作者单位：[1]Department of Obstetrics and Gynecology, Aviation General Hospital, Chaoyang District, Beijing, China
共同第一作者：
通讯作者：
通讯机构：[4]Cancer Center of the First Hospital of Jilin University,Changchun, Jilin 130021,China[42]Department of Nutrition, Daping Hospital & Research Institute of Surgery, Third Military Medical University, Chongqing 400042, China[43]Department of Gastrointestinal Surgery, Department of Clinical Nutrition, Beijing Shijitan Hospital, Capital Medical University/The 9th Clinical Medical College, Peking University, Beijing 100038, China
推荐引用方式(GB/T 7714)：
Wen Ying Li,Guo Lan Gao,Chun Hua Song,等.肿瘤营养学杂志（英文）.2017,2(3):145-152.
