Current antitumor treatment methods have several reported limitations, including multidrug resistance and serious adverse reactions. Targeted drug delivery systems are effective alternatives that can help healthcare providers overcome these limitations. Exosomes can serve as a natural nanoscale drug delivery system, with the advantages of high biocompatibility, low immunogenicity, and efficient tumor targetability. In this paper, we discuss the biological characteristics of exosomes, summarize the drug-carrying mechanisms of exosome-based drug delivery systems, and examine the potential role and applicability of exosomes in clinical tumor treatment approaches. This review can be used as a guideline for the future development of exosome-based delivery systems in clinical precision tumor treatment.
基金：
Natural Science Foundation of Hubei Province of China [2021CFB348]
第一作者单位：[1]Huazhong Univ Sci & Technol, Tongji Hosp, Tongji Med Coll, Dept Pharm, Wuhan, Peoples R China
通讯作者：
推荐引用方式(GB/T 7714)：
Fu Wei,Li Tingting,Chen Hongbo,et al.Research Progress in Exosome-Based Nanoscale Drug Carriers in Tumor Therapies[J].FRONTIERS IN ONCOLOGY.2022,12:doi:10.3389/fonc.2022.919279.
APA：
Fu, Wei,Li, Tingting,Chen, Hongbo,Zhu, Shu&Zhou, Changkai.(2022).Research Progress in Exosome-Based Nanoscale Drug Carriers in Tumor Therapies.FRONTIERS IN ONCOLOGY,12,
MLA：
Fu, Wei,et al."Research Progress in Exosome-Based Nanoscale Drug Carriers in Tumor Therapies".FRONTIERS IN ONCOLOGY 12.(2022)
