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Evaluation of modified cold-atmospheric pressure plasma (MCAP) for the treatment of peri-implantitis in beagles.

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收录情况： ◇ SCIE

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单位： [1]Department of Stomatology, Baoan Maternal and Child Health Hospital, Jinan University, Shenzhen, China. [2]Department of Stomatology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

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关键词： cold atmosphere plasma dental implants interleukin modified peri-implantitis

摘要：

To assess the effect of adjunctive use of modified cold-atmospheric pressure plasma (MCAP) to surgically mechanical debridement (MD) on peri-implantitis (PI) in beagles.Bilateral mandibles of beagles with PI, which induced by cotton ligature twined with steel in sub-marginal around the implant, were randomly divided into two groups: MD in conjunction with 2% CHX irrigation (control group) and MD with adjunctive intervention of MCAP (plasma group). Sulcus bleeding index (SBI), probing depth (PD) and bone height (BH) were examined before and after intervention using computed tomography and histological staining. Additionally, interleukin (IL)-1β, IL-6 and IL-17 levels in peri-implant sulcular fluid (PISF) were measured by ELISA.A significant improvement in SBI, PD and BH was found in the plasma group (p < .05) when compared with the control group after three months of intervention. In addition, IL-1β and IL-17, but not IL-6 levels decreased (p < .05) in the plasma group compared with the control group after intervention.The adjunctive use of MCAP to MD for PI can enhance bone formation around the implant and inhibit the inflammatory response. The application of MCAP could be considered a favourable adjunct to MD for PI.© 2020 Wiley Periodicals LLC.

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中科院(CAS)分区：

出版当年[2021]版：

大类 | 3 区医学

小类 | 3 区牙科与口腔外科

最新[2025]版：

大类 | 3 区医学

小类 | 4 区牙科与口腔外科

JCR分区：

出版当年[2020]版：

Q1 DENTISTRY, ORAL SURGERY & MEDICINE

最新[2023]版：

Q1 DENTISTRY, ORAL SURGERY & MEDICINE

影响因子： 2.9 最新[2023版] 3.4 最新五年平均 3.511 出版当年[2020版] 3.722 出版当年五年平均 2.613 出版前一年[2019版] 4.068 出版后一年[2021版]

第一作者：

第一作者单位： [1]Department of Stomatology, Baoan Maternal and Child Health Hospital, Jinan University, Shenzhen, China. [*1]Department of Stomatology, Baoan Maternal and Child Health Hospital, Jinan University, Shenzhen, Guangdong, China

通讯作者：

通讯机构： [1]Department of Stomatology, Baoan Maternal and Child Health Hospital, Jinan University, Shenzhen, China. [*1]Department of Stomatology, Baoan Maternal and Child Health Hospital, Jinan University, Shenzhen, Guangdong, China

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Evaluation of modified cold-atmospheric pressure plasma (MCAP) for the treatment of peri-implantitis in beagles.

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